3-((Methylsulfonyl)oxy)azetidine-1-carboxylic acid tert-butyl ester
1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine
CAS: 141699-58-3
Molecular Formula: C9H17NO5S
3-((Methylsulfonyl)oxy)azetidine-1-carboxylic acid tert-butyl ester - Names and Identifiers
3-((Methylsulfonyl)oxy)azetidine-1-carboxylic acid tert-butyl ester - Physico-chemical Properties
| Molecular Formula | C9H17NO5S |
| Molar Mass | 251.3 |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Melting Point | 69 °C |
| Boling Point | 378.5±31.0 °C(Predicted) |
| Flash Point | 182.731°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Light yellow |
| pKa | -4.18±0.40(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.504 |
3-((Methylsulfonyl)oxy)azetidine-1-carboxylic acid tert-butyl ester - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
| Hazard Class | IRRITANT |
3-((Methylsulfonyl)oxy)azetidine-1-carboxylic acid tert-butyl ester - Introduction
1-Boc-3-(methylsulfonyloxy) azetidine is an organic compound with the chemical name (S)-Boc-3-(methylsulfonyloxy)pentan-1-amine. It is a white solid, stable at room temperature. The compound has a certain solubility, soluble in some organic solvents, such as dichloromethane and ethanol. It is a strong basic functional group, which can be removed by deprotection reaction under acidic conditions.
1-Boc-3-(methylsulfonyloxy) azetidine is widely used as an intermediate in organic synthesis. It can generate various functional compounds by substitution reaction, condensation reaction and amination reaction. One important use is in the synthesis of drugs. For example, an anticancer drug can be synthesized by a substitution reaction of 1-Boc-3-(methylsulfonyloxy) azetidine.
1-Boc-3-(methanesulfonyloxy) azetidine is generally prepared by reacting 3-hydroxyazetidine with methanesulfonyl chloride to obtain a methanesulfonylated product, which is then subjected to a condensation reaction with a Boc-protecting agent to obtain the target product.
However, note the safety information for this compound. When using the need to pay attention to protective measures, such as wearing gloves, protective glasses and protective clothing. Avoid inhalation, ingestion or contact with skin and eyes as it may be irritating to the skin and eyes. In addition, it should be stored in a dry place, away from fire and oxidizing agents.
1-Boc-3-(methylsulfonyloxy) azetidine is widely used as an intermediate in organic synthesis. It can generate various functional compounds by substitution reaction, condensation reaction and amination reaction. One important use is in the synthesis of drugs. For example, an anticancer drug can be synthesized by a substitution reaction of 1-Boc-3-(methylsulfonyloxy) azetidine.
1-Boc-3-(methanesulfonyloxy) azetidine is generally prepared by reacting 3-hydroxyazetidine with methanesulfonyl chloride to obtain a methanesulfonylated product, which is then subjected to a condensation reaction with a Boc-protecting agent to obtain the target product.
However, note the safety information for this compound. When using the need to pay attention to protective measures, such as wearing gloves, protective glasses and protective clothing. Avoid inhalation, ingestion or contact with skin and eyes as it may be irritating to the skin and eyes. In addition, it should be stored in a dry place, away from fire and oxidizing agents.
Last Update：2024-04-09 20:52:54
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Product Name: 1-(Tert-Butoxycarbonyl)-3-(Methanesulfonyloxy)Azetidine Visit Supplier Webpage Request for quotation
CAS: 141699-58-3
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CAS: 141699-58-3
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
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